Pomegranate’s cardiovascular benefits are not from generic antioxidant activity. They come primarily from punicalagins, a unique class of ellagitannin polyphenols found almost exclusively in pomegranate.
Research shows punicalagins reduce LDL oxidation (a key atherosclerosis trigger), improve endothelial function, reduce blood pressure in hypertensive subjects and provide potent anti-inflammatory effects in cardiovascular tissue.
Punicalagins are hydrolyzed to ellagic acid and then metabolized to urolithins by gut bacteria. These urolithins have their own biological activity including anti-inflammatory and anti-aging properties. Gut microbiome composition affects individual response.
We include Pomegranate Extract for cardiovascular antioxidant support alongside CoQ10. Two complementary mechanisms protecting your heart from different angles. See our full benefits.